Developing Optimized Folding Interfering Degraders Targeting Cyclin D1
Time: 11:10 am
day: Conference Day 2
Details:
• Providing an overview of folding interference as a new modality to induce the degradation of a target protein
• Demonstrating that folding interfering degraders (FIDs) can be optimized to achieve high potency and desirable ADME properties
• Showing in vitro and in vivo characterization of FIDs acting on Cyclin D1