Discovery of Novel E3 Ligands for Targeted Protein Degradation
Time: 2:00 pm
day: Conference Day 1
Details:
• Discussing how cullin-RING E3 ligases (CRLs) are better suited for developing novel E3 ligands due to their multi-subunit assembly mechanism and intrinsic structural flexibility
• What factors to consider for the selection of E3 ligases for developing E3 ligands?
• Updating on discovery of novel E3 ligands at Cullgen